HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: PRDX1 (Q06830)
Peroxiredoxin-1 (EC 1.11.1.24) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Thioredoxin-dependent peroxiredoxin 1)
Gene: PRDX1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	17909037
Identification Methods	anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 920 Hs			1 199
+	Hs
		520003 ANDR_HUMAN (1-920): 0: 966: 100.00		PRDX4_HUMAN (4-197): 4.05e-95: 279: 69.59
+	Hs
		395579 ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20		PRDX2_HUMAN (1-198): 2.39e-103: 297: 77.78
+	Hs
		395558 ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20		PRDX3_HUMAN (2-197): 1.86e-98: 287: 62.76
+	Hs
		396027 ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20		PRDX4_HUMAN (4-197): 4.05e-95: 279: 69.59
+	Rn
		443603 GCR_RAT (444-920): 1.6e-112: 365: 40.04		PRDX1_RAT (1-199): 1.37e-105: 303: 97.49
+	Hs
		403850 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		PRDX3_HUMAN (2-197): 1.86e-98: 287: 62.76
+	Hs
		732372 ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51		PRDX2_HUMAN (1-198): 2.39e-103: 297: 77.78
+	Hs
		442928 PRGR_HUMAN (469-920): 4.73e-106: 352: 45.73		PRDX1_HUMAN (1-199): 2.22e-105: 302: 100.00
+	Hs
		716594 ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51		PRDX3_HUMAN (2-197): 1.86e-98: 287: 62.76
+	Hs
		1097018 ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51		PRDX4_HUMAN (4-197): 4.05e-95: 279: 69.59
+	Hs
		395555 ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20		PRDX6_HUMAN (4-197): 5.87e-67: 206: 28.50
+	Hs
		652503 NR4A1_HUMAN (410-905): 1.86e-106: 343: 18.71		PRDX4_HUMAN (4-197): 4.05e-95: 279: 69.59
+	Hs
		716331 ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51		PRDX6_HUMAN (4-197): 5.87e-67: 206: 28.50
+	Hs
		520520 RARA_HUMAN (460-902): 8.61e-110: 348: 19.87		PRDX6_HUMAN (4-197): 5.87e-67: 206: 28.50
+	Hs
		652452 NR4A1_HUMAN (410-905): 1.86e-106: 343: 18.71		PRDX6_HUMAN (4-197): 5.87e-67: 206: 28.50
+	Hs
		716292 HNF4G_HUMAN (559-900): 2.72e-98: 315: 23.39		PRDX6_HUMAN (4-197): 5.87e-67: 206: 28.50