HitPredict

Interactor 1: TCPA (P12612)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha)
Gene: TCP1

Interactor 2: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	23041314, 9878052, 21701561
Identification Methods	biochemical, anti tag coimmunoprecipitation, molecular sieving, cross-linking study
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 559 Sc			1 375
+	Hs
		826692 TCPG_HUMAN (4-555): 0: 575: 29.53		ACTBL_HUMAN (2-375): 0: 687: 83.42
+	Hs
		1122486 TCPH_HUMAN (4-556): 0: 555: 31.78		ACTBL_HUMAN (2-375): 0: 687: 83.42
+	Hs
		821244 TCPE_HUMAN (17-552): 0: 530: 29.31		ACTBL_HUMAN (2-375): 0: 687: 83.42
+	Hs
		826593 TCPG_HUMAN (4-555): 0: 575: 29.53		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		826609 TCPG_HUMAN (4-555): 0: 575: 29.53		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Hs
		573194 TCPA_HUMAN (9-556): 0: 569: 62.23		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		573210 TCPA_HUMAN (9-556): 0: 569: 62.23		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Hs
		826611 TCPG_HUMAN (4-555): 0: 575: 29.53		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		573212 TCPA_HUMAN (9-556): 0: 569: 62.23		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		891991 TCPH_HUMAN (4-556): 0: 555: 31.78		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		929984 TCPH_HUMAN (4-556): 0: 555: 31.78		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Hs
		932351 TCPH_HUMAN (4-556): 0: 555: 31.78		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Sc
		760791 TCPG_YEAST (7-552): 0: 537: 28.75		ACT_YEAST (1-375): 0: 594: 100.00
+	Hs
		821144 TCPE_HUMAN (17-552): 0: 530: 29.31		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		821160 TCPE_HUMAN (17-552): 0: 530: 29.31		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Sc
		792394 TCPH_YEAST (1-555): 0: 531: 31.00		ACT_YEAST (1-375): 0: 594: 100.00
+	Hs
		821162 TCPE_HUMAN (17-552): 0: 530: 29.31		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		821163 TCPE_HUMAN (17-552): 0: 530: 29.31		ACTS_HUMAN (2-375): 0: 590: 86.90
+	Hs
		821155 TCPE_HUMAN (17-552): 0: 530: 29.31		ACTA_HUMAN (2-375): 0: 589: 86.63