Interactor 1: BMP2 (P12643)
Bone morphogenetic protein 2 (BMP-2) (Bone morphogenetic protein 2A) (BMP-2A)
Gene: BMP2

Interactor 2: RGMA (Q96B86)
Repulsive guidance molecule A (RGM domain family member A)
Gene: RGMA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 25938661
Identification Methods surface plasmon resonance, x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains RGM_C~TGF_beta, RGM_N~TGF_beta
Common GO terms GO:0009986 - cell surface
GO:0030509 - BMP signaling pathway
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 396
Hs

1 450
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024