HitPredict

Interactor 1: HLAC (P10321)
HLA class I histocompatibility antigen, C alpha chain (HLA-C) (HLA-Cw) (Human leukocyte antigen C)
Gene: HLA-C

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 366 Hs			1 196
+	Hs
		409343 HLAA_HUMAN (1-365): 2.57e-175: 493: 81.37		RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10
+	Hs
		409334 HLAA_HUMAN (1-365): 2.57e-175: 493: 81.37		RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67
+	Hs
		409342 HLAA_HUMAN (1-365): 2.57e-175: 493: 81.37		RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00
+	Hs
		409244 HLAA_HUMAN (1-365): 2.57e-175: 493: 81.37		RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57
+	Hs
		409350 HLAA_HUMAN (1-365): 2.57e-175: 493: 81.37		RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53
+	Hs
		409225 HLAA_HUMAN (1-365): 2.57e-175: 493: 81.37		RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16
+	Hs
		409331 HLAA_HUMAN (1-365): 2.57e-175: 493: 81.37		RAC3_HUMAN (1-179): 5.41e-75: 225: 57.54
+	Hs
		409332 HLAA_HUMAN (1-365): 2.57e-175: 493: 81.37		CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49
+	Hs
		409252 HLAA_HUMAN (1-365): 2.57e-175: 493: 81.37		RHOQ_HUMAN (2-195): 6.74e-68: 207: 51.74
+	Hs
		126431 HLAA_HUMAN (1-365): 2.57e-175: 493: 81.37		RHOD_HUMAN (7-182): 3.38e-66: 203: 53.98
+	Hs
		379984 HLAB_HUMAN (1-363): 1.8e-155: 442: 85.95		RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67
+	Hs
		520806 HLAC_HUMAN (1-366): 7.07e-154: 439: 100.00		RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10
+	Hs
		520803 HLAC_HUMAN (1-366): 7.07e-154: 439: 100.00		RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67
+	Hs
		520735 HLAC_HUMAN (1-366): 7.07e-154: 439: 100.00		RAC2_HUMAN (1-196): 4.54e-77: 230: 53.57
+	Hs
		466079 HLAC_HUMAN (1-366): 7.07e-154: 439: 100.00		RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16
+	Hs
		520799 HLAC_HUMAN (1-366): 7.07e-154: 439: 100.00		RAC3_HUMAN (1-179): 5.41e-75: 225: 57.54
+	Hs
		520801 HLAC_HUMAN (1-366): 7.07e-154: 439: 100.00		CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49
+	Hs
		607357 HLAG_HUMAN (1-337): 2.56e-151: 431: 78.64		CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49