HitPredict

Interactor 1: A1Z6Z9 (A1Z6Z9)
Dilute class unconventional myosin, isoform A
Gene: didum

Interactor 2: ACT3 (P53501)
Actin-57B (EC 3.6.4.-)
Gene: Act57B

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Myosin_head
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0015629 - actin cytoskeleton
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1792 Dm			1 376
+	Hs
		993397 MYO5A_HUMAN (3-1790): 0: 1091: 37.80		ACTG_HUMAN (3-376): 0: 604: 94.92
+	Hs
		993344 MYO5C_HUMAN (3-1792): 0: 1009: 35.28		ACTG_HUMAN (3-376): 0: 604: 94.92
+	Hs
		995837 MYO5C_HUMAN (3-1792): 0: 1009: 35.28		ACTC_HUMAN (2-376): 0: 599: 92.53
+	Sc
		738106 MYO4_YEAST (6-1053): 0: 865: 37.18		ACT_YEAST (1-376): 0: 593: 87.50
+	Hs
		953118 MYO10_HUMAN (5-1021): 0: 853: 29.99		ACTB_HUMAN (3-376): 0: 605: 95.46
+	Hs
		993339 MYO10_HUMAN (5-1021): 0: 853: 29.99		ACTG_HUMAN (3-376): 0: 604: 94.92
+	Sp
		314218 MYO52_SCHPO (7-990): 0: 632: 38.15		ACT_SCHPO (3-376): 0: 595: 89.31
+	Sc
		623922 MYO2_YEAST (996-1790): 7.24e-31: 135: 12.81		ACT_YEAST (1-376): 0: 593: 87.50
+	Mm
		953280 MYH9_MOUSE (728-1330): 5.97e-27: 122: 10.77		ACTB_MOUSE (3-376): 0: 605: 95.46
+	Rn
		953303 MYH9_RAT (728-1330): 5.77e-26: 119: 11.40		ACTB_RAT (3-376): 0: 605: 95.46
+	Mm
		977876 MYH6_MOUSE (791-1313): 2.64e-19: 97.5: 10.20		ACTA_MOUSE (1-376): 0: 596: 92.31