HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: AKAP6 (Q13023)
A-kinase anchor protein 6 (AKAP-6) (A-kinase anchor protein 100 kDa) (AKAP 100) (Protein kinase A-anchoring protein 6) (PRKA6) (mAKAP)
Gene: AKAP6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17110338
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0071320 - cellular response to cAMP
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 2319
+	Hs
		529088 CFTR_HUMAN (1-1480): 0: 1031: 100.00		SPTN1_HUMAN (913-1371): 1.2e-24: 115: 12.58
+	Hs
		529896 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH13_HUMAN (827-1357): 1.34e-24: 115: 9.88
+	Hs
		528984 CFTR_HUMAN (1-1480): 0: 1031: 100.00		SPTB2_HUMAN (620-1335): 3.36e-22: 107: 8.79
+	Hs
		528675 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH9_HUMAN (877-1373): 1.07e-19: 99.3: 10.37
+	Hs
		513826 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DMD_HUMAN (790-1253): 8.01e-19: 96.5: 14.08
+	Hs
		529003 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DYST_HUMAN (268-1371): 1.25e-12: 76.2: 11.00
+	Hs
		529917 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MACF1_HUMAN (492-1238): 6.54e-11: 70.8: 10.98