HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: DAZ4 (Q86SG3)
Deleted in azoospermia protein 4
Gene: DAZ4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	35156780
Identification Methods	protein complementation assay, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0032991 - protein-containing complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 579
+	Hs
		529709 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP3_HUMAN (1-489): 1.22e-47: 177: 11.32
+	Hs
		529773 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DAZ3_HUMAN (280-579): 6.25e-43: 162: 72.33
+	Hs
		529541 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP5_HUMAN (1-119): 3.88e-22: 100: 22.90
+	Hs
		529544 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DAZP1_HUMAN (13-165): 6.05e-20: 94.2: 25.00
+	Hs
		516343 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP1_HUMAN (1-208): 2.08e-15: 81.6: 13.10
+	Hs
		528552 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ROA2_HUMAN (3-119): 4.02e-12: 69.8: 29.41
+	Hs
		529172 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ELAV1_HUMAN (199-284): 9.93e-12: 68.4: 25.84
+	Hs
		453113 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ROA1_HUMAN (3-121): 4.37e-11: 66.7: 26.45
+	Hs
		529069 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP4_HUMAN (195-286): 2.17e-09: 62.4: 17.90
+	Hs
		529208 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PAP1L_HUMAN (195-286): 4.06e-09: 61.2: 14.74
+	Sc
		376791 YCFI_YEAST (748-1433): 4.8e-56: 216: 14.59		PABP_YEAST (19-513): 5.84e-52: 189: 13.62