HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: SRSF2 (Q01130)
Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)
Gene: SRSF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 221
+	Hs
		529852 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		SF3B4_HUMAN (4-205): 3.92e-52: 175: 17.24
+	Hs
		529716 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		ELAV2_HUMAN (1-195): 3.76e-37: 134: 15.79
+	Hs
		529736 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PABP4_HUMAN (5-191): 3.38e-24: 101: 13.37
+	Hs
		530532 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PUF60_HUMAN (8-108): 8.36e-24: 100: 23.76
+	Mm
		530835 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		SRSF2_MOUSE (1-221): 1.23e-43: 147: 100.00
+	Mm
		530834 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		Q62029_MOUSE (6-198): 2.14e-38: 142: 18.65
+	Hs
		529183 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		TIA1_HUMAN (9-182): 8.58e-16: 76.9: 10.73
+	Hs
		529799 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		ELAV3_HUMAN (115-195): 2.56e-11: 63.8: 11.11
+	Rn
		620110 TAU_RAT (1-758): 3.21e-76: 263: 72.11		PUF60_RAT (8-108): 8.45e-24: 100: 23.76
+	Hs
		528957 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PABP1_HUMAN (104-194): 9.81e-11: 62.7: 9.89
+	Mm
		530733 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		TIA1_MOUSE (7-184): 4.43e-16: 77.7: 11.67
+	Rn
		620098 TAU_RAT (1-758): 3.21e-76: 263: 72.11		PABP1_RAT (104-194): 1.06e-10: 62.3: 9.89
+	Rn
		98792 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		PABP1_RAT (104-194): 1.06e-10: 62.3: 9.89
+	Hs
		550367 KMT2C_HUMAN (228-752): 7.28e-09: 62: 7.94		PABP1_HUMAN (104-194): 9.81e-11: 62.7: 9.89