HitPredict

Interactor 1: TAU (P10637)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: SRSF2 (Q62093)
Serine/arginine-rich splicing factor 2 (Protein PR264) (Putative myelin regulatory factor 1) (MRF-1) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)
Gene: SRSF2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30068389
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 733 Mm			1 221
+	Mm
		530834 TAU_MOUSE (1-733): 2.37e-87: 292: 100.00		Q62029_MOUSE (6-198): 2.14e-38: 142: 18.65
+	Hs
		529852 TAU_HUMAN (1-733): 5e-62: 223: 69.69		SF3B4_HUMAN (4-205): 3.92e-52: 175: 17.24
+	Hs
		529647 TAU_HUMAN (1-733): 5e-62: 223: 69.69		SRSF2_HUMAN (1-221): 1.23e-43: 147: 100.00
+	Rn
		620110 TAU_RAT (1-733): 4.65e-79: 270: 88.06		PUF60_RAT (8-108): 8.45e-24: 100: 23.76
+	Mm
		530733 TAU_MOUSE (1-733): 2.37e-87: 292: 100.00		TIA1_MOUSE (7-184): 4.43e-16: 77.7: 11.67
+	Hs
		529716 TAU_HUMAN (1-733): 5e-62: 223: 69.69		ELAV2_HUMAN (1-195): 3.76e-37: 134: 15.79
+	Rn
		620098 TAU_RAT (1-733): 4.65e-79: 270: 88.06		PABP1_RAT (104-194): 1.06e-10: 62.3: 9.89
+	Rn
		98792 F1LST4_RAT (1-732): 7.83e-79: 270: 88.18		PABP1_RAT (104-194): 1.06e-10: 62.3: 9.89
+	Hs
		529736 TAU_HUMAN (1-733): 5e-62: 223: 69.69		PABP4_HUMAN (5-191): 3.38e-24: 101: 13.37
+	Hs
		530532 TAU_HUMAN (1-733): 5e-62: 223: 69.69		PUF60_HUMAN (8-108): 8.36e-24: 100: 23.76
+	Hs
		529183 TAU_HUMAN (1-733): 5e-62: 223: 69.69		TIA1_HUMAN (9-182): 8.58e-16: 76.9: 10.73
+	Hs
		529799 TAU_HUMAN (1-733): 5e-62: 223: 69.69		ELAV3_HUMAN (115-195): 2.56e-11: 63.8: 11.11
+	Hs
		528957 TAU_HUMAN (1-733): 5e-62: 223: 69.69		PABP1_HUMAN (104-194): 9.81e-11: 62.7: 9.89
+	Hs
		1102033 ATX2L_HUMAN (23-632): 8.89e-27: 119: 11.68		PABP4_HUMAN (5-191): 3.38e-24: 101: 13.37
+	Hs
		550378 ATX2L_HUMAN (23-632): 8.89e-27: 119: 11.68		PABP1_HUMAN (104-194): 9.81e-11: 62.7: 9.89
+	Hs
		1030690 ANK2_HUMAN (120-695): 2.29e-25: 115: 17.02		PABP3_HUMAN (104-194): 8.31e-09: 56.9: 9.89