HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ARMC8 (Q8IUR7)
Armadillo repeat-containing protein 8
Gene: ARMC8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32812023
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 673
+	Hs
		142481 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		IMA3_HUMAN (132-580): 2.49e-43: 165: 12.34
+	Hs
		253579 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		IMA7_HUMAN (152-547): 2.33e-34: 139: 13.22
+	Hs
		179021 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		IMA6_HUMAN (389-673): 1.01e-32: 134: 17.30
+	Hs
		529388 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		IMA1_HUMAN (14-276): 2.02e-28: 121: 15.47
+	Hs
		529389 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		IMA5_HUMAN (152-547): 6.79e-28: 120: 13.22
+	Hs
		138622 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		IMA4_HUMAN (30-355): 2.81e-24: 109: 12.63
+	Hs
		142611 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		IMA3_HUMAN (132-580): 2.49e-43: 165: 12.34
+	Hs
		911062 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		IMA1_HUMAN (14-276): 2.02e-28: 121: 15.47
+	Hs
		911348 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		IMA5_HUMAN (152-547): 6.79e-28: 120: 13.22
+	Hs
		138755 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		IMA4_HUMAN (30-355): 2.81e-24: 109: 12.63