HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: JKIP1 (Q96N16)
Janus kinase and microtubule-interacting protein 1 (GABA-B receptor-binding protein) (Multiple alpha-helices and RNA-linker protein 1) (Marlin-1)
Gene: JAKMIP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0008017 - microtubule binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 626
+	Hs
		530150 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MY18A_HUMAN (64-625): 2.2e-19: 95.4: 9.11
+	Hs
		67527 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYH7B_HUMAN (72-617): 5.49e-15: 81.2: 12.79
+	Hs
		530549 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYH2_HUMAN (293-624): 3.35e-12: 72.1: 13.55
+	Hs
		529216 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYH9_HUMAN (275-626): 2.11e-11: 69.4: 11.65
+	Hs
		269432 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		KI21B_HUMAN (7-611): 3.51e-11: 68.6: 14.40
+	Hs
		529217 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYH10_HUMAN (275-626): 4.89e-11: 68.3: 10.80
+	Hs
		529988 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		WDR87_HUMAN (73-604): 5.31e-11: 68.2: 13.21
+	Hs
		530422 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MYO5C_HUMAN (39-551): 2.69e-10: 65.9: 14.37
+	Hs
		529006 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		DESP_HUMAN (6-568): 1.72e-09: 63.2: 13.76
+	Rn
		620102 TAU_RAT (1-758): 3.21e-76: 263: 72.11		MYH10_RAT (1-373): 4.77e-11: 68.3: 12.03
+	Rn
		98796 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		MYH10_RAT (1-373): 4.77e-11: 68.3: 12.03
+	Hs
		158047 PCLO_HUMAN (21-757): 4.9e-30: 130: 10.00		CTRO_HUMAN (21-602): 2.17e-23: 107: 15.64
+	Ce
		145076 UNC89_CAEEL (4-460): 1.4e-21: 103: 12.35		MYSP_CAEEL (98-624): 1.1e-20: 98.7: 8.33
+	Hs
		157378 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		CTRO_HUMAN (21-602): 2.17e-23: 107: 15.64
+	Hs
		551605 NFH_HUMAN (113-708): 1.12e-25: 115: 10.96		MYH9_HUMAN (275-626): 2.11e-11: 69.4: 11.65
+	Dm
		1039713 CPN_DROME (353-756): 7.79e-12: 70.8: 13.55		Q9VTY8_DROME (2-512): 1.89e-11: 69.5: 18.81
+	Dm
		122290 CPN_DROME (353-756): 7.79e-12: 70.8: 13.55		M9PI41_DROME (2-512): 1.92e-11: 69.5: 18.81
+	Hs
		587777 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		DESP_HUMAN (6-568): 1.72e-09: 63.2: 13.76