HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: HYOU1 (Q9Y4L1)
Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) (Heat shock protein family H member 4)
Gene: HYOU1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005739 - mitochondrion GO:0051087 - protein-folding chaperone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 999
+	Hs
		530146 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		343883 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		HS74L_HUMAN (33-960): 0: 792: 24.57
+	Hs
		529204 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Mm
		530829 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		HS105_MOUSE (33-970): 0: 818: 24.84
+	Rn
		312680 TAU_RAT (1-758): 3.21e-76: 263: 72.11		HSP74_RAT (33-964): 0: 787: 25.53
+	Rn
		98642 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		HSP74_RAT (33-964): 0: 787: 25.53
+	Mm
		530726 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		HS74L_MOUSE (33-955): 0: 795: 25.24
+	Mm
		530801 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		Q3U2G2_MOUSE (33-964): 0: 780: 25.11
+	Hs
		590251 MUC1_HUMAN (39-730): 2.41e-41: 165: 11.50		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		529203 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		HS71L_HUMAN (682-816): 2.75e-30: 129: 14.82
+	Hs
		516148 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		HS71A_HUMAN (682-813): 9.61e-30: 128: 16.67
+	Hs
		528943 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		HSP7C_HUMAN (682-815): 6.77e-30: 128: 16.42
+	Hs
		529415 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		HSP72_HUMAN (682-814): 3.96e-29: 126: 16.54
+	Hs
		529020 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		HSP76_HUMAN (682-813): 1.24e-26: 118: 19.70
+	Mm
		530698 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		HS71L_MOUSE (682-816): 2.3e-30: 130: 15.56
+	Mm
		530769 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		HSP7C_MOUSE (682-815): 5.77e-30: 129: 16.42
+	Mm
		530699 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		HSP72_MOUSE (682-814): 1.09e-28: 124: 15.79
+	Mm
		530828 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		HS71A_MOUSE (682-813): 5.36e-28: 123: 15.91
+	Hs
		551608 NFH_HUMAN (113-708): 1.12e-25: 115: 10.96		HSP72_HUMAN (682-814): 3.96e-29: 126: 16.54
+	Hs
		536553 MAP4_HUMAN (22-721): 3.01e-10: 66.2: 9.24		HSP7C_HUMAN (682-815): 6.77e-30: 128: 16.42