HitPredict

Interactor 1: P4HA1 (P13674)
Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1)
Gene: P4HA1

Interactor 2: CO8A1 (P27658)
Collagen alpha-1(VIII) chain (Endothelial collagen) [Cleaved into: Vastatin]
Gene: COL8A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005788 - endoplasmic reticulum lumen
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 534 Hs			1 744
+	Hs
		180007 P4HA2_HUMAN (1-534): 0: 695: 61.61		CO8A1_HUMAN (1-744): 2.55e-82: 279: 100.00
+	Hs
		180041 P4HA2_HUMAN (1-534): 0: 695: 61.61		Q4VAQ0_HUMAN (435-743): 6.44e-39: 151: 54.37
+	Hs
		441052 P4HA1_HUMAN (1-534): 0: 716: 100.00		CO4A2_HUMAN (300-656): 1.54e-20: 99.6: 28.79
+	Hs
		532118 P4HA1_HUMAN (1-534): 0: 716: 100.00		CO4A6_HUMAN (318-650): 6.28e-19: 94.2: 27.71
+	Hs
		358594 P4HA1_HUMAN (1-534): 0: 716: 100.00		CO2A1_HUMAN (11-281): 2.59e-15: 82.6: 21.43
+	Hs
		180006 P4HA2_HUMAN (1-534): 0: 695: 61.61		CO8A2_HUMAN (13-360): 7.22e-16: 83.8: 25.38
+	Hs
		358463 P4HA1_HUMAN (1-534): 0: 716: 100.00		CO1A1_HUMAN (10-209): 3.78e-09: 62.6: 21.10
+	Hs
		179997 P4HA2_HUMAN (1-534): 0: 695: 61.61		CO1A1_HUMAN (10-209): 3.78e-09: 62.6: 21.10