Protein: TXK
Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)

Gene: TXK
Organism: Homo sapiens
Interactions: 34
UniProt ID: P42681

Gene Ontology (top 5):
GO:0001819 - positive regulation of cytokine production
GO:0002250 - adaptive immune response
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

155921

SOCS3
Suppressor of cytokine signaling 3

2

20

High-throughput

0.783

High

156012

SOCS6
Suppressor of cytokine signaling 6

2

19

High-throughput

0.783

High

222026

NCK2
Cytoplasmic protein NCK2

2

20

High-throughput

0.783

High

699629

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

20

High-throughput

0.783

High

840908

CRK
Adapter molecule crk

2

20

High-throughput

0.783

High

840909

GRB2
Growth factor receptor-bound protein 2

2

19

High-throughput

0.783

High

840910

GRB10
Growth factor receptor-bound protein 10

2

20

High-throughput

0.783

High

840919

TENS4
Tensin-4

2

20

High-throughput

0.783

High

410690

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

20

High-throughput

0.778

High

641512

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

20

High-throughput

0.778

High

840917

CLNK
Cytokine-dependent hematopoietic cell linker

2

20

High-throughput

0.743

High

472018

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

532057

KIT
Mast/stem cell growth factor receptor Kit

1

20

High-throughput

0.692

High

840922

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

20

High-throughput

0.691

High

362925

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.647

High

840912

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

249726

DOK2
Docking protein 2

2

20

High-throughput

0.606

High

840911

IKZF1
DNA-binding protein Ikaros

2

5

High-throughput

0.606

High

840913

DUS6
Dual specificity protein phosphatase 6

2

8

High-throughput

0.606

High

840914

ZN792
Zinc finger protein 792

2

3

High-throughput

0.606

High

840923

ZN587
Zinc finger protein 587

2

5

High-throughput

0.606

High

840925

PRD14
PR domain zinc finger protein 14

2

2

High-throughput

0.606

High

840926

IKZF4
Zinc finger protein Eos

2

7

High-throughput

0.606

High

840928

RBAK
RB-associated KRAB zinc finger protein

2

2

High-throughput

0.606

High

840929

STAP2
Signal-transducing adaptor protein 2

2

3

High-throughput

0.606

High

840930

ZN835
Zinc finger protein 835

2

4

High-throughput

0.606

High

840915

H90B4
Putative heat shock protein HSP 90-beta 4

1

20

High-throughput

0.575

High

840920

CCD33
Coiled-coil domain-containing protein 33

1

2

High-throughput

0.555

High

840924

AASD1
Alanyl-tRNA editing protein Aarsd1

1

1

High-throughput

0.536

High

286798

JERKY
Jerky protein homolog

1

0

High-throughput

0.493

High

840918

HOMEZ
Homeobox and leucine zipper protein Homez

1

7

High-throughput

0.481

High

840927

CHM4B
Charged multivesicular body protein 4b

1

2

High-throughput

0.479

High

840916

EFHC2
EF-hand domain-containing family member C2

2

0

High-throughput

0.316

High

840921

CBY2
Protein chibby homolog 2

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025