HitPredict

Interactor 1: TWIST (P13903)
Twist-related protein (T18) (X-twist)
Gene: twist1

Interactor 2: TWIST (P13903)
Twist-related protein (T18) (X-twist)
Gene: twist1

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19950203
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0014029 - neural crest formation GO:0046983 - protein dimerization activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 166 Xl			1 166
+	Hs
		1076842 TWST1_HUMAN (1-166): 1.27e-37: 129: 61.88		TWST1_HUMAN (1-166): 1.27e-37: 129: 61.88
+	Hs
		1076849 TWST1_HUMAN (1-166): 1.27e-37: 129: 61.88		TWST2_HUMAN (2-166): 2.59e-38: 129: 78.79
+	Rn
		600265 Q9EPJ1_RAT (1-166): 8.49e-38: 129: 63.05		TFE2_RAT (1-166): 4.98e-25: 102: 22.34
+	Mm
		550182 TWST1_MOUSE (1-166): 2.6e-37: 128: 62.14		TFE2_MOUSE (1-166): 8.91e-25: 101: 22.87
+	Hs
		1261462 TWST2_HUMAN (2-166): 2.59e-38: 129: 78.79		FER3L_HUMAN (61-136): 1.8e-26: 99.8: 41.56
+	Hs
		551530 TWST1_HUMAN (1-166): 1.27e-37: 129: 61.88		TFE2_HUMAN (6-166): 8.11e-24: 98.8: 22.70
+	Hs
		551559 TWST2_HUMAN (2-166): 2.59e-38: 129: 78.79		TFE2_HUMAN (6-166): 8.11e-24: 98.8: 22.70
+	Dm
		496113 TWIST_DROME (2-158): 5.69e-28: 109: 35.94		TWIST_DROME (2-158): 5.69e-28: 109: 35.94
+	Hs
		526750 MYF5_HUMAN (4-149): 5.64e-31: 114: 19.60		SCX_HUMAN (15-139): 1.29e-26: 101: 33.33
+	Hs
		551472 MYF6_HUMAN (2-143): 6.5e-32: 116: 19.01		TFE2_HUMAN (6-166): 8.11e-24: 98.8: 22.70
+	Hs
		526739 MYF5_HUMAN (4-149): 5.64e-31: 114: 19.60		TFE2_HUMAN (6-166): 8.11e-24: 98.8: 22.70
+	Mm
		192773 TCF21_MOUSE (2-153): 2.27e-29: 107: 30.72		TFE2_MOUSE (1-166): 8.91e-25: 101: 22.87
+	Mm
		485933 MYOD1_MOUSE (23-144): 5.34e-27: 104: 20.33		MYOD1_MOUSE (23-144): 5.34e-27: 104: 20.33
+	Mm
		485935 MYOD1_MOUSE (23-144): 5.34e-27: 104: 20.33		TFE2_MOUSE (1-166): 8.91e-25: 101: 22.87
+	Hs
		551565 NGN1_HUMAN (4-139): 1.05e-27: 104: 27.70		TFE2_HUMAN (6-166): 8.11e-24: 98.8: 22.70
+	Hs
		551577 NDF4_HUMAN (64-131): 7.97e-27: 104: 42.03		TFE2_HUMAN (6-166): 8.11e-24: 98.8: 22.70
+	Hs
		551515 TCF15_HUMAN (18-139): 1.51e-27: 103: 35.77		TFE2_HUMAN (6-166): 8.11e-24: 98.8: 22.70
+	Hs
		210857 TCF21_HUMAN (2-153): 1.47e-27: 102: 30.07		TFE2_HUMAN (6-166): 8.11e-24: 98.8: 22.70
+	Hs
		210855 TCF21_HUMAN (2-153): 1.47e-27: 102: 30.07		MYOD1_HUMAN (23-131): 9.04e-24: 96.4: 20.91