HitPredict

Interactor 1: EDN3 (P14138)
Endothelin-3 (ET-3) (Preproendothelin-3) (PPET3)
Gene: EDN3

Interactor 2: LAMB3 (Q13751)
Laminin subunit beta-3 (Epiligrin subunit bata) (Kalinin B1 chain) (Kalinin subunit beta) (Laminin B1k chain) (Laminin-5 subunit beta) (Nicein subunit beta)
Gene: LAMB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 238 Hs			1 1172
+	Hs
		535630 EDN3_HUMAN (1-238): 3.65e-155: 431: 100.00		NOTC2_HUMAN (255-723): 8.86e-43: 173: 15.05
+	Hs
		535624 EDN3_HUMAN (1-238): 3.65e-155: 431: 100.00		LAMB2_HUMAN (449-748): 1.04e-15: 84.9: 14.54
+	Hs
		172641 EDN3_HUMAN (1-238): 3.65e-155: 431: 100.00		LAMA5_HUMAN (152-326): 1.32e-12: 74.9: 15.51
+	Hs
		535622 EDN3_HUMAN (1-238): 3.65e-155: 431: 100.00		NOTC1_HUMAN (432-707): 5.63e-11: 69.5: 13.84