HitPredict

Interactor 1: TA2R (P21731)
Thromboxane A2 receptor (TXA2-R) (Prostanoid TP receptor)
Gene: TBXA2R

Interactor 2: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	15782186, 12399457
Identification Methods	fluorescent resonance energy transfer, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	7tm_1~WD40
Common GO terms	GO:0005886 - plasma membrane GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 343 Hs			1 340
+	Hs
		429007 ADRB2_HUMAN (1-331): 4.89e-64: 210: 12.57		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		429006 ADRB2_HUMAN (1-331): 4.89e-64: 210: 12.57		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		429130 ADRB2_HUMAN (1-331): 4.89e-64: 210: 12.57		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88
+	Rn
		495780 ADRB2_RAT (1-332): 8.07e-64: 209: 12.81		GNB5_RAT (129-340): 1.48e-45: 160: 21.92