HitPredict

Interactor 1: HCLS1 (P14317)
Hematopoietic lineage cell-specific protein (Hematopoietic cell-specific LYN substrate 1) (LckBP1) (p75)
Gene: HCLS1

Interactor 2: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol and 1 others more... GO:0005886 - plasma membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 486 Hs			1 140
+	Hs
		742294 SRC8_HUMAN (1-486): 5.55e-127: 382: 39.86		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Hs
		580950 PLCG1_HUMAN (55-485): 1.1e-40: 158: 17.41		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Hs
		742595 DBNL_HUMAN (144-486): 1.31e-35: 138: 26.01		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00