HitPredict

Interactor 1: INSRR (P14616)
Insulin receptor-related protein (IRR) (EC 2.7.10.1) (IR-related receptor) [Cleaved into: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]
Gene: INSRR

Interactor 2: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030424 - axon
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1297 Hs			1 450
+	Hs
		435747 IGF1R_HUMAN (9-1265): 0: 1222: 55.39		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		411272 INSR_HUMAN (27-1288): 0: 1183: 52.18		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		428109 EPHA4_HUMAN (455-1279): 0: 609: 20.55		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		872631 EPHA4_HUMAN (455-1279): 0: 609: 20.55		TBB4B_HUMAN (1-427): 0: 703: 93.91
+	Hs
		872702 EPHA4_HUMAN (455-1279): 0: 609: 20.55		TBB2B_HUMAN (1-430): 0: 703: 93.72
+	Hs
		872701 EPHA4_HUMAN (455-1279): 0: 609: 20.55		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		381152 EPHA4_HUMAN (455-1279): 0: 609: 20.55		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Hs
		1072512 EPHA7_HUMAN (454-1280): 0: 598: 20.58		TBB8_HUMAN (1-427): 0: 705: 87.59
+	Hs
		428222 EPHA7_HUMAN (454-1280): 0: 598: 20.58		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		934024 ALK_HUMAN (946-1247): 1.07e-70: 263: 43.46		TBB4B_HUMAN (1-427): 0: 703: 93.91
+	Hs
		384794 NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		384107 NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		384633 NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91		TBB4B_HUMAN (1-427): 0: 703: 93.91
+	Hs
		385452 NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91		TBB2B_HUMAN (1-430): 0: 703: 93.72
+	Hs
		385445 NTRK1_HUMAN (957-1247): 1.28e-65: 240: 42.91		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		1081592 NTRK3_HUMAN (957-1242): 2.05e-62: 231: 40.84		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		508174 FGFR1_HUMAN (948-1294): 6.81e-59: 221: 35.90		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		381109 FGFR1_HUMAN (948-1294): 6.81e-59: 221: 35.90		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Hs
		601930 ERBB3_HUMAN (2-296): 3.16e-34: 145: 18.24		TBB8_HUMAN (1-427): 0: 705: 87.59
+	Hs
		428019 ERBB3_HUMAN (2-296): 3.16e-34: 145: 18.24		TBB5_HUMAN (1-429): 0: 704: 93.94