Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP
Interactor 2: TF7L2 (Q9NQB0)
Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (hTCF-4)
Gene: TCF7L2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.72 | 1.00 | 0.849 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 11711551, unassigned1304 |
| Identification Methods | two hybrid, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Arm~CTNNB1_binding, Arm~HMG_box |
| Common GO terms | GO:0005634 - nucleus GO:0032993 - protein-DNA complex GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0060070 - canonical Wnt signaling pathway |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
