HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: SWD3 (P38123)
COMPASS component SWD3 (Complex proteins associated with SET1 protein SWD3) (Set1C component SWD3)
Gene: SWD3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	16554755, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000723 - telomere maintenance
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 315
+	Hs
		438414 HS90B_HUMAN (5-705): 0: 1022: 61.15		FBXW7_HUMAN (1-308): 2.78e-72: 237: 18.91
+	Hs
		432132 HS90A_HUMAN (4-705): 0: 1013: 60.67		FBXW7_HUMAN (1-308): 2.78e-72: 237: 18.91
+	Hs
		438048 HS90B_HUMAN (5-705): 0: 1022: 61.15		WDR5_HUMAN (4-216): 3.22e-55: 184: 19.09
+	Ca
		483034 HSP90_CANAL (4-705): 0: 953: 82.36		TUP1_CANAL (2-216): 6.36e-56: 190: 21.46
+	Hs
		538344 ENPL_HUMAN (3-680): 0: 893: 47.10		FBXW7_HUMAN (1-308): 2.78e-72: 237: 18.91
+	Sc
		543602 HSC82_YEAST (1-705): 0: 977: 100.00		TAF5_YEAST (88-312): 9.22e-37: 141: 20.90
+	Cr
		65491 A8J1U1_CHLRE (4-705): 0: 1002: 63.17		MUT11_CHLRE (157-313): 2.27e-27: 111: 17.50
+	Sc
		366167 HSP82_YEAST (1-705): 0: 968: 95.63		TAF5_YEAST (88-312): 9.22e-37: 141: 20.90
+	Hs
		437971 HS90B_HUMAN (5-705): 0: 1022: 61.15		LIS1_HUMAN (231-314): 8.47e-12: 67.4: 19.77
+	Hs
		431630 HS90A_HUMAN (4-705): 0: 1013: 60.67		LIS1_HUMAN (231-314): 8.47e-12: 67.4: 19.77
+	Hs
		538184 ENPL_HUMAN (3-680): 0: 893: 47.10		WDR5_HUMAN (4-216): 3.22e-55: 184: 19.09
+	Sc
		365738 HSP82_YEAST (1-705): 0: 968: 95.63		TUP1_YEAST (89-312): 1.66e-20: 93.9: 17.16
+	Sc
		365880 HSP82_YEAST (1-705): 0: 968: 95.63		PWP2_YEAST (54-233): 4.21e-16: 80.9: 26.92
+	Sc
		544430 HSC82_YEAST (1-705): 0: 977: 100.00		UTP13_YEAST (72-227): 3.21e-09: 60.1: 28.21
+	Sc
		366904 HSP82_YEAST (1-705): 0: 968: 95.63		UTP13_YEAST (72-227): 3.21e-09: 60.1: 28.21
+	Hs
		538141 ENPL_HUMAN (3-680): 0: 893: 47.10		LIS1_HUMAN (231-314): 8.47e-12: 67.4: 19.77