HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: PPID (P53691)
Peptidyl-prolyl cis-trans isomerase CPR6 (PPIase CPR6) (EC 5.2.1.8) (Rotamase CPR6)
Gene: CPR6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	25380751, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0042026 - protein refolding GO:0051082 - unfolded protein binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 371
+	Sc
		819388 SSB2_YEAST (1-613): 0: 1118: 99.35		PPID_YEAST (1-371): 2.93e-121: 356: 100.00
+	Sc
		545414 SSB1_YEAST (1-613): 0: 1128: 100.00		CYP7_YEAST (1-371): 8.22e-93: 284: 37.88
+	Sc
		819150 SSB2_YEAST (1-613): 0: 1118: 99.35		CYP7_YEAST (1-371): 8.22e-93: 284: 37.88
+	Sc
		543998 SSB1_YEAST (1-613): 0: 1128: 100.00		CYPC_YEAST (5-171): 5.86e-78: 239: 56.29
+	Sc
		543678 SSB1_YEAST (1-613): 0: 1128: 100.00		CYPH_YEAST (5-171): 3.89e-78: 238: 56.29
+	Sc
		575951 SSB2_YEAST (1-613): 0: 1118: 99.35		CYPH_YEAST (5-171): 3.89e-78: 238: 56.29
+	Hs
		537045 HSP7C_HUMAN (5-612): 0: 901: 59.84		PPID_HUMAN (2-371): 8.42e-131: 381: 43.51
+	Sc
		481671 HSP73_YEAST (9-611): 0: 928: 60.66		CYP7_YEAST (1-371): 8.22e-93: 284: 37.88
+	Sc
		481511 HSP73_YEAST (9-611): 0: 928: 60.66		CYPC_YEAST (5-171): 5.86e-78: 239: 56.29
+	Hs
		536579 HSP7C_HUMAN (5-612): 0: 901: 59.84		PPIF_HUMAN (3-174): 5.53e-78: 240: 54.07
+	Ca
		835803 HSP71_CANAL (9-594): 0: 670: 63.37		PPID_CANAL (1-371): 1.01e-119: 352: 51.07
+	Sc
		645752 HSP74_YEAST (9-611): 0: 681: 62.15		CYP7_YEAST (1-371): 8.22e-93: 284: 37.88
+	Sc
		645692 HSP74_YEAST (9-611): 0: 681: 62.15		CYPC_YEAST (5-171): 5.86e-78: 239: 56.29