HitPredict

Interactor 1: KPYM (P11980)
Pyruvate kinase PKM (EC 2.7.1.40) (Pyruvate kinase muscle isozyme) (Threonine-protein kinase PKM2) (EC 2.7.11.1) (Tyrosine-protein kinase PKM2) (EC 2.7.10.2)
Gene: Pkm

Interactor 2: KPYM (P11980)
Pyruvate kinase PKM (EC 2.7.1.40) (Pyruvate kinase muscle isozyme) (Threonine-protein kinase PKM2) (EC 2.7.11.1) (Tyrosine-protein kinase PKM2) (EC 2.7.10.2)
Gene: Pkm

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 9990017
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK~PK, PK~PK_C, PK_C~PK_C
Common GO terms GO:0000287 - magnesium ion binding
GO:0001666 - response to hypoxia
GO:0001889 - liver development
GO:0003729 - mRNA binding
GO:0004713 - protein tyrosine kinase activity
and 28 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 531
Rn

1 531
+ Hs
+ Oc
+ Hs
+ Hs
+ Ce
+ Ce
+ Ce
+ Ce
+ Sc
+ Sc
+ At
+ At
+ Ec

Service provided by Combinatics, Japan

Last updated: 11Aug2025