HitPredict

Interactor 1: DESP (P15924)
Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)
Gene: DSP

Interactor 2: PKP2 (Q99959)
Plakophilin-2
Gene: PKP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 0.60 0.608

The method score is based on:

Property Details
Experiments 11790773, 25225338
Identification Methods affinity chromatography technology, two hybrid, fluorescence microscopy
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001533 - cornified envelope
GO:0002934 - desmosome organization
GO:0005080 - protein kinase C binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 10 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 2871
Hs

1 881
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024