HitPredict

Interactor 1: TCPA (P12612)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha)
Gene: TCP1

Interactor 2: GBB (P18851)
Guanine nucleotide-binding protein subunit beta
Gene: STE4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	11805837
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 559 Sc			1 423
+	Hs
		882038 TCPG_HUMAN (4-555): 0: 575: 29.53		POC1A_HUMAN (4-297): 5.9e-81: 256: 14.24
+	Hs
		610775 TCPA_HUMAN (9-556): 0: 569: 62.23		POC1A_HUMAN (4-297): 5.9e-81: 256: 14.24
+	Hs
		882119 TCPG_HUMAN (4-555): 0: 575: 29.53		TBL1Y_HUMAN (162-422): 7.23e-51: 181: 16.21
+	Hs
		610855 TCPA_HUMAN (9-556): 0: 569: 62.23		TBL1Y_HUMAN (162-422): 7.23e-51: 181: 16.21
+	Hs
		163619 TCPG_HUMAN (4-555): 0: 575: 29.53		GNB5_HUMAN (163-420): 8.82e-38: 143: 15.58
+	Hs
		882051 TCPG_HUMAN (4-555): 0: 575: 29.53		POC1B_HUMAN (4-164): 6.22e-37: 142: 12.88
+	Hs
		881865 TCPG_HUMAN (4-555): 0: 575: 29.53		GBB2_HUMAN (216-420): 7.16e-37: 139: 19.72
+	Hs
		163610 TCPA_HUMAN (9-556): 0: 569: 62.23		GNB5_HUMAN (163-420): 8.82e-38: 143: 15.58
+	Hs
		610789 TCPA_HUMAN (9-556): 0: 569: 62.23		POC1B_HUMAN (4-164): 6.22e-37: 142: 12.88
+	Hs
		610605 TCPA_HUMAN (9-556): 0: 569: 62.23		GBB2_HUMAN (216-420): 7.16e-37: 139: 19.72
+	Hs
		882075 TCPG_HUMAN (4-555): 0: 575: 29.53		FBXW7_HUMAN (256-423): 1.11e-32: 132: 20.12
+	Hs
		610813 TCPA_HUMAN (9-556): 0: 569: 62.23		FBXW7_HUMAN (256-423): 1.11e-32: 132: 20.12
+	Hs
		845257 TCPG_HUMAN (4-555): 0: 575: 29.53		LIS1_HUMAN (340-420): 1.07e-19: 92.5: 23.46
+	Hs
		881861 TCPG_HUMAN (4-555): 0: 575: 29.53		WDR5_HUMAN (324-422): 2.17e-19: 90.5: 20.20
+	Hs
		882014 TCPG_HUMAN (4-555): 0: 575: 29.53		WDR5B_HUMAN (323-420): 7.17e-18: 85.9: 20.41
+	Hs
		610601 TCPA_HUMAN (9-556): 0: 569: 62.23		WDR5_HUMAN (324-422): 2.17e-19: 90.5: 20.20
+	Hs
		610750 TCPA_HUMAN (9-556): 0: 569: 62.23		WDR5B_HUMAN (323-420): 7.17e-18: 85.9: 20.41
+	Hs
		610819 TCPA_HUMAN (9-556): 0: 569: 62.23		SNR40_HUMAN (1-118): 2.32e-14: 75.9: 10.57
+	Hs
		881864 TCPG_HUMAN (4-555): 0: 575: 29.53		GBB1_HUMAN (340-420): 7.46e-11: 65.2: 17.28
+	Hs
		610604 TCPA_HUMAN (9-556): 0: 569: 62.23		GBB1_HUMAN (340-420): 7.46e-11: 65.2: 17.28