Interactor 1: FGFR1 (P16092)
Fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (MFR) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: KLOTB (Q99N32)
Beta-klotho (BKL) (BetaKlotho) (Klotho beta-like protein)
Gene: Klb

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 17623664, 17452648
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Glyco_hydro_1~I-set
Common GO terms GO:0005886 - plasma membrane
GO:0008284 - positive regulation of cell population proliferation
GO:0008543 - fibroblast growth factor receptor signaling pathway
GO:0017134 - fibroblast growth factor binding
GO:0090080 - positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 822
Mm

1 1043
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Ce

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Last updated: 15 Jul 2024