HitPredict

Interactor 1: SYF1 (A1Z9G2)
Pre-mRNA-splicing factor syf1 homolog (Pre-mRNA-splicing factor fandango) (Protein faint sausage)
Gene: fand

Interactor 2: Q9VD52 (Q9VD52)
Pre-mRNA-processing factor 17 (Cell division cycle 40 homolog) (PRP17 homolog)
Gene: CDC40

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0071011 - precatalytic spliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 883 Dm			1 576
+	Sp
		207284 SYF1_SCHPO (15-798): 2.11e-149: 461: 41.83		PRP17_SCHPO (18-576): 2.61e-106: 332: 36.75
+	Dm
		55550 SYF1_DROME (1-883): 0: 613: 100.00		Q9VPL0_DROME (444-576): 5.6e-27: 113: 17.29
+	Hs
		1387577 SYF1_HUMAN (26-873): 0: 550: 61.15		SNR40_HUMAN (446-576): 1.88e-30: 124: 22.14
+	Hs
		1439440 SYF1_HUMAN (26-873): 0: 550: 61.15		PRP19_HUMAN (280-484): 1.37e-17: 87.8: 25.96
+	Sc
		829957 SYF1_YEAST (16-731): 2.47e-85: 293: 21.38		PRP17_YEAST (139-576): 5.35e-98: 307: 33.71
+	Dm
		609125 CRN_DROME (1-518): 3.23e-35: 145: 13.85		Q9VD52_DROME (1-576): 1.3e-150: 446: 100.00
+	Sp
		207263 CLF1_SCHPO (7-560): 1.98e-37: 152: 14.19		PRP17_SCHPO (18-576): 2.61e-106: 332: 36.75
+	Sc
		829967 CLF1_YEAST (181-854): 3.12e-36: 148: 15.11		PRP17_YEAST (139-576): 5.35e-98: 307: 33.71
+	Hs
		845302 SART3_HUMAN (20-493): 1.58e-33: 141: 14.97		LIS1_HUMAN (89-403): 7.46e-47: 171: 12.97
+	Hs
		1227473 NRDE2_HUMAN (7-767): 1.26e-57: 217: 11.59		A16L1_HUMAN (273-565): 4.55e-16: 83.6: 27.15
+	Hs
		1092342 CSTF3_HUMAN (23-600): 7.32e-42: 165: 12.66		SNR40_HUMAN (446-576): 1.88e-30: 124: 22.14
+	Hs
		1387547 CRNL1_HUMAN (1-519): 3.27e-38: 155: 12.73		SNR40_HUMAN (446-576): 1.88e-30: 124: 22.14
+	Dm
		609146 CRN_DROME (1-518): 3.23e-35: 145: 13.85		Q9VPL0_DROME (444-576): 5.6e-27: 113: 17.29
+	Hs
		964957 SART3_HUMAN (20-493): 1.58e-33: 141: 14.97		WDR5_HUMAN (70-356): 3.37e-26: 111: 13.61
+	Hs
		1092323 CSTF3_HUMAN (23-600): 7.32e-42: 165: 12.66		A16L1_HUMAN (273-565): 4.55e-16: 83.6: 27.15
+	Hs
		1419983 CRNL1_HUMAN (1-519): 3.27e-38: 155: 12.73		PRP19_HUMAN (280-484): 1.37e-17: 87.8: 25.96
+	Hs
		1227406 CRNL1_HUMAN (1-519): 3.27e-38: 155: 12.73		A16L1_HUMAN (273-565): 4.55e-16: 83.6: 27.15
+	Hs
		1227213 TTC28_HUMAN (75-776): 8.47e-34: 143: 7.73		A16L1_HUMAN (273-565): 4.55e-16: 83.6: 27.15
+	Hs
		185575 OGT1_HUMAN (482-792): 1.11e-24: 113: 11.64		WDR5_HUMAN (70-356): 3.37e-26: 111: 13.61
+	Hs
		185769 OGT1_HUMAN (482-792): 1.11e-24: 113: 11.64		A16L1_HUMAN (273-565): 4.55e-16: 83.6: 27.15