HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: KAT2B (Q92831)
Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) (Spermidine acetyltransferase KAT2B) (EC 2.3.1.57)
Gene: KAT2B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	20224553
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005813 - centrosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 143 Hs			1 832
+	Mm
		1151749 H2A2A_MOUSE (1-129): 7e-66: 197: 91.47		KAT2B_MOUSE (1-832): 0: 1161: 91.13
+	Hs
		391825 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		KAT2B_HUMAN (72-832): 0: 1128: 100.00
+	Hs
		555569 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		KAT2A_HUMAN (63-832): 0: 1056: 73.42
+	Hs
		391824 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		KAT2A_HUMAN (63-832): 0: 1056: 73.42
+	Hs
		555681 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BAZ2A_HUMAN (698-826): 7.81e-38: 155: 35.66
+	Hs
		555299 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BRD2_HUMAN (663-830): 1.89e-35: 146: 23.37
+	Hs
		555434 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BPTF_HUMAN (725-825): 5.43e-35: 146: 47.53
+	Hs
		555470 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BRD3_HUMAN (672-830): 6.16e-33: 138: 22.67
+	Hs
		631492 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		BRD2_HUMAN (663-830): 1.89e-35: 146: 23.37
+	Mm
		70932 H2A3_MOUSE (1-129): 5.88e-66: 197: 91.47		EP300_MOUSE (664-825): 2.37e-35: 147: 23.03
+	Hs
		391554 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		BRD2_HUMAN (663-830): 1.89e-35: 146: 23.37
+	Hs
		1067038 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		BRD3_HUMAN (672-830): 6.16e-33: 138: 22.67
+	Hs
		1067005 H2A2A_HUMAN (1-129): 7e-66: 197: 91.47		BRD3_HUMAN (672-830): 6.16e-33: 138: 22.67
+	Hs
		1066979 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		BRD3_HUMAN (672-830): 6.16e-33: 138: 22.67
+	Hs
		244848 H2A1J_HUMAN (1-128): 1.45e-66: 199: 92.19		BRD4_HUMAN (680-832): 1.99e-31: 134: 22.15
+	Hs
		244634 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		BRD4_HUMAN (680-832): 1.99e-31: 134: 22.15
+	Hs
		244795 H2A1H_HUMAN (1-128): 2.85e-66: 198: 92.19		BRD4_HUMAN (680-832): 1.99e-31: 134: 22.15
+	Hs
		243783 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		BRD4_HUMAN (680-832): 1.99e-31: 134: 22.15
+	Hs
		555528 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		PB1_HUMAN (683-826): 4.92e-18: 91.8: 22.00
+	Hs
		391768 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		PB1_HUMAN (683-826): 4.92e-18: 91.8: 22.00