HitPredict

Interactor 1: PSA1 (P12881)
Proteasome subunit alpha type-1 (PROS-Dm35) (Proteasome 35 kDa subunit)
Gene: Prosalpha6

Interactor 2: TERA (Q7KN62)
Transitional endoplasmic reticulum ATPase TER94 (EC 3.6.4.6) (Valosin-containing protein homolog)
Gene: TER94

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA_lid_3~Proteasome, AAA~Proteasome_A_N, AAA_lid_3~Proteasome_A_N
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 279 Dm			1 801
+	Dm
		652749 PSA71_DROME (4-236): 4.11e-102: 299: 30.93		TERA_DROME (1-801): 0: 764: 100.00
+	Dm
		1267908 PSA5_DROME (1-240): 3.08e-93: 277: 28.11		TERA_DROME (1-801): 0: 764: 100.00
+	Hs
		680826 PSA1_HUMAN (1-269): 1.17e-102: 301: 52.42		TERA_HUMAN (2-800): 0: 739: 81.57
+	Hs
		700593 PSA5_HUMAN (1-239): 6.43e-95: 281: 30.08		TERA_HUMAN (2-800): 0: 739: 81.57
+	Hs
		165300 PSA7_HUMAN (6-237): 6.41e-94: 278: 37.02		TERA_HUMAN (2-800): 0: 739: 81.57
+	Hs
		934362 PSA6_HUMAN (1-243): 8.69e-93: 275: 29.48		TERA_HUMAN (2-800): 0: 739: 81.57
+	Hs
		681608 PSA4_HUMAN (1-236): 2.49e-90: 270: 29.22		TERA_HUMAN (2-800): 0: 739: 81.57
+	Sc
		679748 PSA6_YEAST (1-236): 5.88e-67: 209: 46.64		CDC48_YEAST (1-801): 0: 733: 66.67
+	Hs
		700686 PSA5_HUMAN (1-239): 6.43e-95: 281: 30.08		AFG2A_HUMAN (412-748): 1.66e-68: 245: 29.91