HitPredict

Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: MED28 (Q9H204)
Mediator of RNA polymerase II transcription subunit 28 (Endothelial-derived protein 1) (Mediator complex subunit 28) (Merlin and Grb2-interacting cytoskeletal protein) (Magicin) (Tumor angiogenesis marker EG-1)
Gene: MED28

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	16964398, 16899217
Identification Methods	affinity chromatography technology, pull down, peptide array, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 178
+	Hs
		463220 YES_HUMAN (1-536): 0: 594: 73.85		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00
+	Hs
		440724 FYN_HUMAN (1-536): 0: 586: 68.39		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00
+	Hs
		473472 HCK_HUMAN (1-531): 0: 560: 55.18		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00
+	Mm
		813528 FYN_MOUSE (1-536): 0: 586: 68.58		MED28_MOUSE (1-178): 8.49e-99: 284: 94.38
+	Hs
		440205 LCK_HUMAN (75-534): 0: 544: 58.48		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00
+	Hs
		840985 ABL2_HUMAN (11-536): 1.52e-164: 499: 38.85		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00
+	Hs
		1054144 BTK_HUMAN (44-527): 5.9e-153: 454: 34.49		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00
+	Hs
		840897 TEC_HUMAN (83-528): 1.55e-152: 452: 37.36		MED28_HUMAN (1-178): 5.46e-109: 310: 100.00