HitPredict

Interactor 1: PP12 (P12982)
Serine/threonine-protein phosphatase alpha-2 isoform (EC 3.1.3.16)
Gene: Pp1-87B

Interactor 2: Q7KU01 (Q7KU01)
Phosphatase 1 nuclear targeting subunit, isoform D (Phosphatase 1 nuclear targeting subunit, isoform E)
Gene: PNUTS

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.627

Property	Details
Experiments	24204300, 17007873
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 302 Dm			1 1135
+	Dm
		873527 PP11_DROME (1-301): 0: 547: 96.68		Q7KU01_DROME (1-1135): 1.97e-120: 400: 100.00
+	Dm
		1051577 PP13_DROME (1-302): 0: 539: 93.71		Q7KU01_DROME (1-1135): 1.97e-120: 400: 100.00
+	Dm
		873581 PP1B_DROME (1-302): 0: 530: 85.48		Q7KU01_DROME (1-1135): 1.97e-120: 400: 100.00
+	Hs
		786793 PP1G_HUMAN (3-301): 0: 549: 93.31		PP1RA_HUMAN (4-549): 2.02e-31: 135: 16.58
+	Hs
		967929 PP1A_HUMAN (2-301): 0: 549: 92.67		PP1RA_HUMAN (4-549): 2.02e-31: 135: 16.58
+	Hs
		968416 PP1B_HUMAN (1-302): 0: 538: 87.79		PP1RA_HUMAN (4-549): 2.02e-31: 135: 16.58
+	Ce
		876756 GLC7B_CAEEL (3-301): 0: 550: 90.97		MEL28_CAEEL (269-704): 3.81e-16: 86.4: 16.74
+	Hs
		967727 PP1A_HUMAN (2-301): 0: 549: 92.67		MDC1_HUMAN (160-938): 8.17e-16: 85.3: 7.55
+	Hs
		967671 PP1A_HUMAN (2-301): 0: 549: 92.67		ANK2_HUMAN (230-723): 7.28e-15: 82.2: 16.09
+	Ce
		1166060 GLC7A_CAEEL (5-302): 0: 536: 87.25		MEL28_CAEEL (269-704): 3.81e-16: 86.4: 16.74
+	Hs
		287877 PP1G_HUMAN (3-301): 0: 549: 93.31		MYCB2_HUMAN (238-696): 4.37e-12: 73.3: 18.64
+	Dm
		119664 PP1B_DROME (1-302): 0: 530: 85.48		M9PB30_DROME (494-1050): 1.28e-17: 91.3: 10.75
+	Mm
		968189 PP1A_MOUSE (2-301): 0: 550: 92.33		TARA_MOUSE (117-964): 2.98e-11: 70.5: 9.00
+	Dm
		55696 Q8T0U6_DROME (17-302): 0: 516: 87.06		A1Z9J3_DROME (163-933): 7.32e-14: 79.2: 9.73
+	Dm
		121043 PP1B_DROME (1-302): 0: 530: 85.48		M9PEP8_DROME (226-885): 1.9e-09: 64.5: 8.26
+	Hs
		994221 PP2AA_HUMAN (6-302): 1.36e-175: 489: 46.64		MDC1_HUMAN (160-938): 8.17e-16: 85.3: 7.55