Interactor 1: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Interactor 2: PP1RA (Q96QC0)
Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53) (PP1-binding protein of 114 kDa) (Phosphatase 1 nuclear targeting subunit) (p99)
Gene: PPP1R10

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.760

The method score is based on:

Property Details
Experiments 20516061, 12574161, 26186194, 27880917, 28514442, 28330616, 29669786, 10637318, 24981860, 33961781, 15231748
Identification Methods affinity chromatography technology, proximity labelling technology, pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001111 - RNA polymerase II promoter clearance
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008157 - protein phosphatase 1 binding
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
and 4 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 330
Hs

1 940
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025