HitPredict

Interactor 1: PP13 (Q05547)
Serine/threonine-protein phosphatase alpha-3 isoform (EC 3.1.3.16)
Gene: Pp1-13C

Interactor 2: Q7KU01 (Q7KU01)
Phosphatase 1 nuclear targeting subunit, isoform D (Phosphatase 1 nuclear targeting subunit, isoform E)
Gene: PNUTS

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.649

Property	Details
Experiments	17007873, 24204300, 14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 302 Dm			1 1135
+	Dm
		873527 PP11_DROME (1-301): 0: 543: 92.36		Q7KU01_DROME (1-1135): 1.97e-120: 400: 100.00
+	Dm
		559042 PP12_DROME (1-302): 0: 541: 93.71		Q7KU01_DROME (1-1135): 1.97e-120: 400: 100.00
+	Dm
		873581 PP1B_DROME (5-302): 0: 528: 85.57		Q7KU01_DROME (1-1135): 1.97e-120: 400: 100.00
+	Hs
		967929 PP1A_HUMAN (2-301): 0: 549: 91.67		PP1RA_HUMAN (4-549): 2.02e-31: 135: 16.58
+	Hs
		786793 PP1G_HUMAN (3-301): 0: 547: 91.64		PP1RA_HUMAN (4-549): 2.02e-31: 135: 16.58
+	Hs
		968416 PP1B_HUMAN (5-302): 0: 537: 88.93		PP1RA_HUMAN (4-549): 2.02e-31: 135: 16.58
+	Ce
		876756 GLC7B_CAEEL (2-301): 0: 550: 89.67		MEL28_CAEEL (269-704): 3.81e-16: 86.4: 16.74
+	Hs
		967727 PP1A_HUMAN (2-301): 0: 549: 91.67		MDC1_HUMAN (160-938): 8.17e-16: 85.3: 7.55
+	Hs
		967671 PP1A_HUMAN (2-301): 0: 549: 91.67		ANK2_HUMAN (230-723): 7.28e-15: 82.2: 16.09
+	Ce
		1166060 GLC7A_CAEEL (5-302): 0: 536: 86.58		MEL28_CAEEL (269-704): 3.81e-16: 86.4: 16.74
+	Hs
		287877 PP1G_HUMAN (3-301): 0: 547: 91.64		MYCB2_HUMAN (238-696): 4.37e-12: 73.3: 18.64
+	Mm
		968189 PP1A_MOUSE (2-301): 0: 549: 91.33		TARA_MOUSE (117-964): 2.98e-11: 70.5: 9.00
+	Dm
		119664 PP1B_DROME (5-302): 0: 528: 85.57		M9PB30_DROME (494-1050): 1.28e-17: 91.3: 10.75
+	Dm
		55696 Q8T0U6_DROME (17-302): 0: 516: 86.71		A1Z9J3_DROME (163-933): 7.32e-14: 79.2: 9.73
+	Dm
		121043 PP1B_DROME (5-302): 0: 528: 85.57		M9PEP8_DROME (226-885): 1.9e-09: 64.5: 8.26