HitPredict

Interactor 1: NR2C1 (P13056)
Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2)
Gene: NR2C1

Interactor 2: MTA1 (Q13330)
Metastasis-associated protein MTA1
Gene: MTA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21670149
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding GO:0042826 - histone deacetylase binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 603 Hs			1 715
+	Hs
		879048 NR2C2_HUMAN (11-603): 4.87e-143: 429: 59.80		MTA1_HUMAN (1-715): 0: 939: 100.00
+	Hs
		316738 NR2C1_HUMAN (1-603): 1.17e-165: 487: 100.00		MTA2_HUMAN (1-715): 0: 741: 57.55
+	Hs
		316781 NR2C2_HUMAN (11-603): 4.87e-143: 429: 59.80		MTA2_HUMAN (1-715): 0: 741: 57.55
+	Hs
		316732 RARA_HUMAN (108-187): 2.87e-27: 117: 60.00		MTA2_HUMAN (1-715): 0: 741: 57.55
+	Hs
		559782 NR2C1_HUMAN (1-603): 1.17e-165: 487: 100.00		RCOR1_HUMAN (165-532): 5.93e-67: 230: 18.60
+	Hs
		1454812 NR2E1_HUMAN (100-259): 3.81e-45: 166: 31.79		RERE_HUMAN (5-654): 1.84e-111: 371: 21.90
+	Hs
		1101145 STF1_HUMAN (106-592): 1.55e-90: 289: 20.74		TREF1_HUMAN (157-346): 5.47e-39: 157: 21.72
+	Hs
		834076 HNF4A_HUMAN (59-228): 7.58e-43: 162: 33.53		RCOR3_HUMAN (167-532): 3.93e-75: 252: 17.71
+	Hs
		1461146 NR2E1_HUMAN (100-259): 3.81e-45: 166: 31.79		RCOR1_HUMAN (165-532): 5.93e-67: 230: 18.60
+	Hs
		833972 HNF4A_HUMAN (59-228): 7.58e-43: 162: 33.53		MDEAS_HUMAN (157-483): 5.97e-46: 178: 14.17
+	Dm
		594750 7UP1_DROME (54-189): 8.1e-40: 154: 44.85		Q86BH2_DROME (161-592): 9.76e-47: 181: 18.83