HitPredict

Interactor 1: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Interactor 2: PININ (Q9H307)
Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein)
Gene: PNN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	28514442, 33961781, 36736316, 23602568
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 499 Hs			1 717
+	Hs
		833818 CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00
+	Hs
		834121 CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00
+	Hs
		625598 CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70		PININ_HUMAN (1-717): 3.37e-144: 440: 100.00