HitPredict

Interactor 1: CCL5 (P13501)
C-C motif chemokine 5 (EoCP) (Eosinophil chemotactic cytokine) (SIS-delta) (Small-inducible cytokine A5) (T cell-specific protein P228) (TCP228) (T-cell-specific protein RANTES) [Cleaved into: RANTES(3-68); RANTES(4-68)]
Gene: CCL5

Interactor 2: XCL2 (Q9UBD3)
Cytokine SCM-1 beta (C motif chemokine 2) (XC chemokine ligand 2)
Gene: XCL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.51 1.00 0.716

The method score is based on:

Property Details
Experiments 28381538
Identification Methods pull down, surface plasmon resonance, filter binding
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IL8~IL8
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006954 - inflammatory response
GO:0008009 - chemokine activity
GO:0030335 - positive regulation of cell migration
and 3 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 91
Hs

1 114
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Service provided by Combinatics, Japan

Last updated: 11Aug2025