Protein: CCL8
C-C motif chemokine 8 (HC14) (Monocyte chemoattractant protein 2) (Monocyte chemotactic protein 2) (MCP-2) (Small-inducible cytokine A8) [Cleaved into: MCP-2(6-76)]

Gene: CCL8
Organism: Homo sapiens
Interactions: 22
UniProt ID: P80075

Gene Ontology (top 5):
GO:0002687 - positive regulation of leukocyte migration
GO:0004672 - protein kinase activity
GO:0005615 - extracellular space
GO:0006816 - calcium ion transport
GO:0006874 - intracellular calcium ion homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

562844

CCL2
C-C motif chemokine 2

2

19

Small-scale

0.802

High

835477

CCR2
C-C chemokine receptor type 2

2

20

Small-scale

0.776

High

906992

CCR5
C-C chemokine receptor type 5

2

20

Small-scale

0.776

High

141830

ACKR2
Atypical chemokine receptor 2

1

20

Small-scale

0.724

High

565097

CSPG2
Versican core protein

1

10

Small-scale

0.724

High

158945

CXL11
C-X-C motif chemokine 11

1

20

High-throughput

0.692

High

390327

CXCL7
Platelet basic protein

1

20

High-throughput

0.692

High

390392

CXL10
C-X-C motif chemokine 10

1

20

High-throughput

0.692

High

518775

IL8
Interleukin-8

1

20

High-throughput

0.692

High

626429

CXCL2
C-X-C motif chemokine 2

1

20

High-throughput

0.692

High

906848

CCL11
Eotaxin

1

19

High-throughput

0.692

High

1009598

CXCL6
C-X-C motif chemokine 6

1

20

High-throughput

0.692

High

1009600

CCL13
C-C motif chemokine 13

1

20

High-throughput

0.692

High

1009602

XCL2
Cytokine SCM-1 beta

1

19

High-throughput

0.692

High

1009603

CCL26
C-C motif chemokine 26

1

19

High-throughput

0.692

High

733327

CCR1
C-C chemokine receptor type 1

1

20

Small-scale

0.665

High

1009601

ACKR4
Atypical chemokine receptor 4

1

20

Small-scale

0.665

High

562887

CCL5
C-C motif chemokine 5

1

18

High-throughput

0.647

High

1009597

CCL8
C-C motif chemokine 8

1

19

Small-scale

0.618

High

1009599

CXL17
C-X-C motif chemokine 17

1

10

High-throughput

0.536

High

814895

MMP12
Macrophage metalloelastase

1

5

Small-scale

0.445

High


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Last updated: 11Aug2025