Protein: CCL22
C-C motif chemokine 22 (CC chemokine STCP-1) (MDC(1-69)) (Macrophage-derived chemokine) (Small-inducible cytokine A22) (Stimulated T-cell chemotactic protein 1) [Cleaved into: MDC(3-69); MDC(5-69); MDC(7-69)]

Gene: CCL22
Organism: Homo sapiens
Interactions: 45
UniProt ID: O00626

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006935 - chemotaxis
GO:0006954 - inflammatory response
GO:0006955 - immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

142205

CCR4
C-C chemokine receptor type 4

1

20

Small-scale

0.747

High

142197

PF4V
Platelet factor 4 variant

1

20

High-throughput

0.692

High

142215

CCL14
C-C motif chemokine 14

1

18

High-throughput

0.692

High

142218

DPP8
Dipeptidyl peptidase 8

2

3

High-throughput

0.628

High

142202

CCR7
C-C chemokine receptor type 7

1

20

Small-scale

0.618

High

142228

CCL19
C-C motif chemokine 19

1

19

Small-scale

0.618

High

142201

DPP4
Dipeptidyl peptidase 4

2

3

Small-scale

0.611

High

142208

RELB
Transcription factor RelB

2

20

Small-scale

0.584

High

142191

PLXA2
Plexin-A2

2

2

High-throughput

0.574

High

142192

KDM4A
Lysine-specific demethylase 4A

2

1

High-throughput

0.574

High

142210

TBB3
Tubulin beta-3 chain

2

6

High-throughput

0.574

High

142212

PDIA5
Protein disulfide-isomerase A5

2

3

High-throughput

0.574

High

142216

LONF2
LON peptidase N-terminal domain and RING finger protein 2

2

1

High-throughput

0.574

High

142217

PREP
Presequence protease, mitochondrial

2

4

High-throughput

0.574

High

142219

DUSTY
Dual serine/threonine and tyrosine protein kinase

2

2

High-throughput

0.574

High

142230

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

2

1

High-throughput

0.574

High

142198

VCAM1
Vascular cell adhesion protein 1

1

1

Small-scale

0.561

High

142211

AQP6
Aquaporin-6

2

1

High-throughput

0.553

High

142196

MET
Hepatocyte growth factor receptor

1

3

High-throughput

0.536

High

142200

FGFR4
Fibroblast growth factor receptor 4

1

3

High-throughput

0.536

High

142207

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.536

High

142214

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

1

High-throughput

0.536

High

142220

CD109
CD109 antigen

1

2

High-throughput

0.536

High

142190

HS12A
Heat shock 70 kDa protein 12A

1

0

High-throughput

0.513

High

142233

LCAP
Leucyl-cystinyl aminopeptidase

1

0

High-throughput

0.513

High

142206

ITA8
Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]

1

1

High-throughput

0.489

High

142199

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

20

Small-scale

0.479

High

142209

TF65
Transcription factor p65

1

20

Small-scale

0.479

High

142226

CNT3B
Contactin-associated protein-like 3B

1

11

High-throughput

0.407

High

142193

RA51D
DNA repair protein RAD51 homolog 4

2

0

High-throughput

0.328

High

142194

GLSK
Glutaminase kidney isoform, mitochondrial

2

0

High-throughput

0.328

High

142221

PRUN1
Exopolyphosphatase PRUNE1

2

0

High-throughput

0.328

High

142222

OAF
Out at first protein homolog

2

0

High-throughput

0.328

High

142223

CHD1L
Chromodomain-helicase-DNA-binding protein 1-like

2

0

High-throughput

0.328

High

142225

EME1
Structure-specific endonuclease subunit EME1

2

0

High-throughput

0.328

High

142227

SPS2
Selenide, water dikinase 2

2

0

High-throughput

0.328

High

142229

F118B
Protein FAM118B

2

0

High-throughput

0.328

High

142232

YTHD1
YTH domain-containing family protein 1

2

0

High-throughput

0.328

High

142195

CRYAB
Alpha-crystallin B chain

1

0

High-throughput

0.282

High

142204

GSH1
Glutamate--cysteine ligase catalytic subunit

1

0

High-throughput

0.282

High

142213

HERC3
Probable E3 ubiquitin-protein ligase HERC3

1

0

High-throughput

0.282

High

142203

PPM1A
Protein phosphatase 1A

1

0

High-throughput

0.279

Low

142224

SEN2
tRNA-splicing endonuclease subunit Sen2

1

0

High-throughput

0.279

Low

142231

ITPA
Inosine triphosphate pyrophosphatase

1

0

High-throughput

0.279

Low

142234

DD19B
ATP-dependent RNA helicase DDX19B

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025