Interactor 1: VATA (P17255)
V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (Vacuolar proton pump subunit A) [Cleaved into: Endonuclease PI-SceI (EC 3.1.-.-) (Sce VMA intein) (VMA1-derived endonuclease) (VDE)]
Gene: VMA1

Interactor 2: VATC (P31412)
V-type proton ATPase subunit C (V-ATPase subunit C) (V-ATPase 42 kDa subunit) (Vacuolar proton pump subunit C)
Gene: VMA5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.727

The method score is based on:

Property Details
Experiments 23142977, 11717306, 37968396, 16429126, 33895134, 23071676
Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology, pull down, unspecified method, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000139 - Golgi membrane
GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0000329 - fungal-type vacuole membrane
GO:0005524 - ATP binding
GO:0007035 - vacuolar acidification
and 6 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1071
Sc

1 392
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Sc
+ Dm
+ Dm
+ Dm

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Last updated: 15 Jul 2024