Protein: CSF1R
Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)

Gene: CSF1R
Organism: Homo sapiens
Interactions: 56
UniProt ID: P07333

Gene Ontology (top 5):
GO:0001934 - positive regulation of protein phosphorylation
GO:0002931 - response to ischemia
GO:0004713 - protein tyrosine kinase activity
GO:0005011 - macrophage colony-stimulating factor receptor activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

456125

CSF1
Macrophage colony-stimulating factor 1

5

3

Small-scale

0.939

High

456140

GRB2
Growth factor receptor-bound protein 2

3

20

Small-scale

0.843

High

193177

SOCS1
Suppressor of cytokine signaling 1

2

20

Small-scale

0.815

High

456151

IL34
Interleukin-34

2

0

Small-scale

0.793

High

456120

CSF1R
Macrophage colony-stimulating factor 1 receptor

2

18

Small-scale

0.778

High

456133

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

20

Small-scale

0.754

High

440297

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.734

High

456127

KIT
Mast/stem cell growth factor receptor Kit

1

18

Small-scale

0.724

High

456132

CBL
E3 ubiquitin-protein ligase CBL

5

20

Small-scale

0.722

High

456126

PGFRB
Platelet-derived growth factor receptor beta

1

19

High-throughput

0.691

High

456135

EPHB2
Ephrin type-B receptor 2

1

20

High-throughput

0.691

High

456146

EPHA7
Ephrin type-A receptor 7

1

20

High-throughput

0.691

High

136256

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

Small-scale

0.647

High

292800

GRAP2
GRB2-related adapter protein 2

1

20

Small-scale

0.647

High

155894

SOCS3
Suppressor of cytokine signaling 3

1

20

Small-scale

0.618

High

456121

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

456122

YES
Tyrosine-protein kinase Yes

1

20

Small-scale

0.618

High

456123

LYN
Tyrosine-protein kinase Lyn

1

20

Small-scale

0.618

High

456124

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

456128

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.618

High

456134

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

456136

SHC1
SHC-transforming protein 1

1

20

Small-scale

0.618

High

456131

SPI1
Transcription factor PU.1

2

2

Small-scale

0.584

High

456149

CDC37
Hsp90 co-chaperone Cdc37

1

11

High-throughput

0.578

High

456160

STAP2
Signal-transducing adaptor protein 2

1

3

Small-scale

0.561

High

158544

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

1

6

High-throughput

0.541

High

456155

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

6

High-throughput

0.541

High

456137

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

20

Small-scale

0.527

High

456144

CUL1
Cullin-1

1

3

High-throughput

0.500

High

456148

NEDD8
Ubiquitin-like protein NEDD8

1

2

High-throughput

0.500

High

456154

PDIP3
Polymerase delta-interacting protein 3

1

1

High-throughput

0.500

High

456163

FBW1A
F-box/WD repeat-containing protein 1A

1

11

High-throughput

0.500

High

456161

FBW1B
F-box/WD repeat-containing protein 11

1

11

High-throughput

0.489

High

169393

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

20

High-throughput

0.479

High

299908

CBPD
Carboxypeptidase D

1

3

High-throughput

0.479

High

330019

VENTX
Homeobox protein VENTX

1

4

Small-scale

0.479

High

336052

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

20

High-throughput

0.479

High

447955

ITAV
Integrin alpha-V

1

7

Small-scale

0.479

High

456129

PDIA4
Protein disulfide-isomerase A4

1

17

High-throughput

0.479

High

456130

CEBPB
CCAAT/enhancer-binding protein beta

1

1

Small-scale

0.479

High

456138

CEBPD
CCAAT/enhancer-binding protein delta

1

4

Small-scale

0.479

High

456139

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

10

Small-scale

0.479

High

456142

SOS1
Son of sevenless homolog 1

1

6

Small-scale

0.479

High

456143

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

1

Small-scale

0.479

High

456156

PDCL3
Phosducin-like protein 3

1

2

Small-scale

0.479

High

456158

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

20

High-throughput

0.479

High

456159

JPH1
Junctophilin-1

1

4

High-throughput

0.479

High

456141

RUNX1
Runt-related transcription factor 1

1

0

Small-scale

0.458

High

456152

YTHD3
YTH domain-containing family protein 3

1

11

High-throughput

0.457

High

456147

TRIPB
Thyroid receptor-interacting protein 11

1

15

High-throughput

0.437

High

456150

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

8

High-throughput

0.437

High

456157

GORS2
Golgi reassembly-stacking protein 2

1

7

High-throughput

0.437

High

456162

KDIS
Kinase D-interacting substrate of 220 kDa

1

8

High-throughput

0.437

High

456145

LAMC2
Laminin subunit gamma-2

1

14

Small-scale

0.408

High

456153

GSTCD
Glutathione S-transferase C-terminal domain-containing protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025