HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 645 Hs			1 802
+	Hs
		541304 PDIA4_HUMAN (1-645): 0: 564: 100.00		FGFR1_HUMAN (3-794): 0: 714: 54.76
+	Hs
		566564 PDIA4_HUMAN (1-645): 0: 564: 100.00		EPHB2_HUMAN (61-781): 0: 589: 18.54
+	Hs
		566563 PDIA4_HUMAN (1-645): 0: 564: 100.00		EPHA8_HUMAN (4-763): 0: 572: 20.10
+	Hs
		566687 PDIA4_HUMAN (1-645): 0: 564: 100.00		NTRK3_HUMAN (159-751): 2.57e-165: 501: 25.24
+	Hs
		411281 PDIA4_HUMAN (1-645): 0: 564: 100.00		NTRK1_HUMAN (135-751): 2.17e-160: 487: 26.53
+	Hs
		463891 PDIA4_HUMAN (1-645): 0: 564: 100.00		RET_HUMAN (221-802): 2.72e-146: 459: 34.72
+	Hs
		566653 PDIA4_HUMAN (1-645): 0: 564: 100.00		MERTK_HUMAN (25-801): 1.76e-144: 452: 21.88
+	Hs
		648432 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		FGFR4_HUMAN (13-802): 0: 755: 100.00
+	Hs
		452140 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		FGFR1_HUMAN (3-794): 0: 714: 54.76
+	Hs
		1156988 DJC10_HUMAN (54-285): 1.12e-46: 178: 21.25		NTRK3_HUMAN (159-751): 2.57e-165: 501: 25.24
+	Hs
		412226 DJC10_HUMAN (54-285): 1.12e-46: 178: 21.25		NTRK1_HUMAN (135-751): 2.17e-160: 487: 26.53
+	Hs
		566572 PDIA4_HUMAN (1-645): 0: 564: 100.00		UFO_HUMAN (29-362): 1.03e-20: 99.8: 16.34
+	Hs
		456129 PDIA4_HUMAN (1-645): 0: 564: 100.00		CSF1R_HUMAN (33-421): 1.6e-12: 73.2: 15.59
+	Hs
		566582 PDIA4_HUMAN (1-645): 0: 564: 100.00		VGFR3_HUMAN (153-356): 9.27e-11: 67.8: 18.78
+	Hs
		566544 PDIA4_HUMAN (1-645): 0: 564: 100.00		VGFR1_HUMAN (26-128): 1.82e-10: 67: 22.22
+	Hs
		411194 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		NTRK1_HUMAN (135-751): 2.17e-160: 487: 26.53
+	Hs
		411429 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		NTRK1_HUMAN (135-751): 2.17e-160: 487: 26.53
+	Hs
		720273 DJC10_HUMAN (54-285): 1.12e-46: 178: 21.25		UFO_HUMAN (29-362): 1.03e-20: 99.8: 16.34
+	Hs
		452187 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		VGFR2_HUMAN (74-376): 3.49e-24: 111: 16.67
+	Hs
		452177 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		UFO_HUMAN (29-362): 1.03e-20: 99.8: 16.34