HitPredict

Interactor 1: CXL10 (P17515)
C-X-C motif chemokine 10 (10 kDa interferon gamma-induced protein) (Gamma-IP10) (IP-10) (C7) (Interferon-gamma induced protein CRG-2) (Small-inducible cytokine B10)
Gene: Cxcl10

Interactor 2: TF65 (Q04207)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: Rela

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15226358
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006954 - inflammatory response GO:0008284 - positive regulation of cell population proliferation GO:0009617 - response to bacterium GO:0016525 - negative regulation of angiogenesis GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 98 Mm			1 549
+	Mm
		500673 CXCL2_MOUSE (15-94): 1.19e-24: 90.5: 25.00		TF65_MOUSE (1-549): 0: 662: 100.00
+	Mm
		522399 GROA_MOUSE (20-91): 2.97e-22: 84.3: 29.17		TF65_MOUSE (1-549): 0: 662: 100.00
+	Hs
		364112 CXL10_HUMAN (1-98): 8.09e-30: 103: 68.37		TF65_HUMAN (1-549): 0: 631: 87.52
+	Hs
		150325 CXL11_HUMAN (1-94): 7.9e-24: 88.6: 35.11		TF65_HUMAN (1-549): 0: 631: 87.52
+	Hs
		587778 CXCL2_HUMAN (19-95): 1.33e-22: 85.5: 28.57		TF65_HUMAN (1-549): 0: 631: 87.52
+	Hs
		486198 IL8_HUMAN (25-92): 1.71e-21: 82.8: 25.00		TF65_HUMAN (1-549): 0: 631: 87.52
+	Hs
		448997 GROA_HUMAN (24-95): 5.85e-21: 81.6: 26.39		TF65_HUMAN (1-549): 0: 631: 87.52
+	Hs
		587791 CXCL3_HUMAN (24-94): 4.97e-21: 81.6: 26.76		TF65_HUMAN (1-549): 0: 631: 87.52
+	Hs
		486199 IL8_HUMAN (25-92): 1.71e-21: 82.8: 25.00		REL_HUMAN (12-491): 8.06e-158: 465: 42.89
+	Hs
		364100 CXL10_HUMAN (1-98): 8.09e-30: 103: 68.37		NFKB1_HUMAN (5-382): 1.19e-142: 437: 32.93
+	Hs
		486197 IL8_HUMAN (25-92): 1.71e-21: 82.8: 25.00		RELB_HUMAN (7-453): 8.96e-153: 451: 39.20
+	Hs
		150310 CXL11_HUMAN (1-94): 7.9e-24: 88.6: 35.11		NFKB1_HUMAN (5-382): 1.19e-142: 437: 32.93
+	Mm
		223018 CXL13_MOUSE (25-98): 1.1e-19: 78.2: 21.62		RELB_MOUSE (13-453): 7.12e-150: 443: 38.54
+	Hs
		486180 IL8_HUMAN (25-92): 1.71e-21: 82.8: 25.00		NFKB1_HUMAN (5-382): 1.19e-142: 437: 32.93
+	Mm
		770720 SDF1_MOUSE (1-95): 4.67e-17: 71.2: 25.26		RELB_MOUSE (13-453): 7.12e-150: 443: 38.54
+	Hs
		486195 IL8_HUMAN (25-92): 1.71e-21: 82.8: 25.00		NFKB2_HUMAN (6-418): 9.56e-141: 430: 33.79