HitPredict

Interactor 1: HS71B (P17879)
Heat shock 70 kDa protein 1B (Heat shock 70 kDa protein 1) (HSP70.1)
Gene: Hspa1b

Interactor 2: BAG4 (Q8CI61)
BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains)
Gene: BAG4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11527400
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAG~HSP70
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 642 Mm			1 457
+	Hs
		314010 HS71L_HUMAN (2-642): 0: 965: 87.21		BAG4_HUMAN (1-457): 2.53e-52: 184: 79.91
+	Hs
		314001 HSP76_HUMAN (3-642): 0: 953: 81.41		BAG4_HUMAN (1-457): 2.53e-52: 184: 79.91
+	Hs
		313996 HSP7C_HUMAN (1-642): 0: 952: 83.75		BAG4_HUMAN (1-457): 2.53e-52: 184: 79.91
+	Hs
		314060 Q53FC7_HUMAN (3-642): 0: 949: 81.09		BAG4_HUMAN (1-457): 2.53e-52: 184: 79.91
+	Hs
		324256 HS71L_HUMAN (2-642): 0: 965: 87.21		BAG3_HUMAN (51-457): 1.42e-30: 126: 22.32
+	Hs
		324216 HSP76_HUMAN (3-642): 0: 953: 81.41		BAG3_HUMAN (51-457): 1.42e-30: 126: 22.32
+	Hs
		324195 HSP7C_HUMAN (1-642): 0: 952: 83.75		BAG3_HUMAN (51-457): 1.42e-30: 126: 22.32
+	Hs
		324190 HS71A_HUMAN (1-642): 0: 951: 94.24		BAG3_HUMAN (51-457): 1.42e-30: 126: 22.32
+	Mm
		571868 HS71B_MOUSE (1-642): 0: 966: 100.00		BAG3_MOUSE (51-457): 1.24e-25: 111: 20.18
+	Hs
		324435 Q53FC7_HUMAN (3-642): 0: 949: 81.09		BAG3_HUMAN (51-457): 1.42e-30: 126: 22.32
+	Mm
		571863 HS71B_MOUSE (1-642): 0: 966: 100.00		BAG5_MOUSE (376-456): 2.31e-25: 109: 38.27
+	Hs
		714093 HS71L_HUMAN (2-642): 0: 965: 87.21		BAG5_HUMAN (376-456): 2.59e-25: 109: 39.51
+	Hs
		564206 HSP76_HUMAN (3-642): 0: 953: 81.41		BAG5_HUMAN (376-456): 2.59e-25: 109: 39.51
+	Mm
		926166 HSP7C_MOUSE (1-642): 0: 951: 83.90		BAG3_MOUSE (51-457): 1.24e-25: 111: 20.18
+	Hs
		504937 HSP7C_HUMAN (1-642): 0: 952: 83.75		BAG5_HUMAN (376-456): 2.59e-25: 109: 39.51
+	Mm
		926151 HSP7C_MOUSE (1-642): 0: 951: 83.90		BAG5_MOUSE (376-456): 2.31e-25: 109: 38.27
+	Hs
		1120596 Q53FC7_HUMAN (3-642): 0: 949: 81.09		BAG5_HUMAN (376-456): 2.59e-25: 109: 39.51
+	Hs
		503711 HSP7C_HUMAN (1-642): 0: 952: 83.75		SMCA2_HUMAN (10-456): 1.77e-15: 81.3: 13.50
+	Dm
		65607 HSP72_DROME (6-642): 0: 949: 75.15		A8JNS4_DROME (347-456): 6.09e-15: 79: 38.18
+	Hs
		503745 HSP7C_HUMAN (1-642): 0: 952: 83.75		SC24C_HUMAN (78-378): 1.39e-09: 62.4: 14.10