Interactor 1: NK1R (P14600)
Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1)
Gene: Tacr1

Interactor 2: OPRM (P33535)
Mu-type opioid receptor (M-OR-1) (MOR-1) (Opioid receptor B)
Gene: Oprm1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 14532289
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~7tm_1
Common GO terms GO:0005886 - plasma membrane
GO:0007218 - neuropeptide signaling pathway
GO:0030425 - dendrite
GO:0042713 - sperm ejaculation
GO:0042755 - eating behavior
and 2 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 407
Rn

1 398
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Last updated: 11Aug2025