Protein: MLXPL
Carbohydrate-responsive element-binding protein (ChREBP) (Class D basic helix-loop-helix protein 14) (bHLHd14) (MLX interactor) (MLX-interacting protein-like) (WS basic-helix-loop-helix leucine zipper protein) (WS-bHLH) (Williams-Beuren syndrome chromosomal region 14 protein)

Gene: MLXPL, MLXIPL
Organism: Homo sapiens
Interactions: 42
UniProt ID: Q9NP71

Gene Ontology (top 5):
GO:0000432 - positive regulation of transcription from RNA polymerase II promoter by glucose
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001216 - DNA-binding transcription activator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1342368

MLX
Max-like protein X

4

17

Small-scale

0.910

High

999115

EP300
Histone acetyltransferase p300

2

15

Small-scale

0.624

High

546047

MYOD1
Myoblast determination protein 1

1

5

Small-scale

0.618

High

163320

XPO1
Exportin-1

2

7

Small-scale

0.584

High

924882

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.481

High

150754

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

10

Small-scale

0.479

High

256429

PHF2
Lysine-specific demethylase PHF2

1

3

Small-scale

0.479

High

339016

EGFR
Epidermal growth factor receptor

1

18

High-throughput

0.479

High

421537

FABPL
Fatty acid-binding protein, liver

1

2

Small-scale

0.479

High

647302

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

787575

MTOR
Serine/threonine-protein kinase mTOR

1

7

Small-scale

0.479

High

799012

GATA4
Transcription factor GATA-4

1

7

Small-scale

0.479

High

826073

FAS
Fatty acid synthase

1

2

Small-scale

0.479

High

857943

PDX1
Pancreas/duodenum homeobox protein 1

1

14

Small-scale

0.479

High

905143

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

917972

H4
Histone H4

1

10

High-throughput

0.479

High

927559

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

959978

TF2B
Transcription initiation factor IIB

1

2

Small-scale

0.479

High

975055

CAV1
Caveolin-1

1

6

Small-scale

0.479

High

982527

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1059888

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

3

Small-scale

0.479

High

1079160

STK11
Serine/threonine-protein kinase STK11

1

1

Small-scale

0.479

High

1082158

CRY1
Cryptochrome-1

1

1

Small-scale

0.479

High

1082405

DDB1
DNA damage-binding protein 1

1

1

Small-scale

0.479

High

1204099

CARM1
Histone-arginine methyltransferase CARM1

1

4

Small-scale

0.479

High

1269687

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1273500

KAT5
Histone acetyltransferase KAT5

1

1

Small-scale

0.479

High

1300894

NR1H4
Bile acid receptor

1

20

Small-scale

0.479

High

1300954

CIC
Protein capicua homolog

1

18

High-throughput

0.479

High

1301581

TRIB1
Tribbles homolog 1

1

3

Small-scale

0.479

High

1334871

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

8

Small-scale

0.479

High

1342367

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

135906

F16P2
Fructose-1,6-bisphosphatase isozyme 2

1

0

Small-scale

0.458

High

602589

COMT
Catechol O-methyltransferase

1

0

Small-scale

0.458

High

727193

DDIT3
DNA damage-inducible transcript 3 protein

1

0

Small-scale

0.458

High

871480

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

0

Small-scale

0.458

High

1199616

LBN
Limbin

1

0

High-throughput

0.458

High

1342365

PLPL3
1-acylglycerol-3-phosphate O-acyltransferase PNPLA3

1

0

Small-scale

0.458

High

1342366

MBD2
Methyl-CpG-binding domain protein 2

1

0

Small-scale

0.458

High

198475

KLK10
Kallikrein-10

1

2

Small-scale

0.437

High

970118

CNTN2
Contactin-2

1

1

Small-scale

0.437

High

1156295

RETST
All-trans-retinol 13,14-reductase

1

5

Small-scale

0.437

High


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Last updated: 15 Jul 2024