HitPredict

Interactor 1: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	26496610, 31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 531 Hs			1 482
+	Hs
		1038670 TCPH_HUMAN (2-530): 0: 576: 27.93		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		770965 TCPZ_HUMAN (1-531): 0: 573: 100.00		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		826651 TCPG_HUMAN (3-528): 0: 559: 27.96		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		826803 TCPG_HUMAN (3-528): 0: 559: 27.96		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		821200 TCPE_HUMAN (3-528): 0: 548: 30.47		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		821342 TCPE_HUMAN (3-528): 0: 548: 30.47		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Sp
		140559 TCPZ_SCHPO (7-530): 0: 639: 63.07		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sc
		693019 TCPZ_YEAST (3-530): 0: 579: 56.75		RPD3_YEAST (8-421): 0: 580: 61.48
+	Hs
		177367 TCPH_HUMAN (2-530): 0: 576: 27.93		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Hs
		177216 TCPZ_HUMAN (1-531): 0: 573: 100.00		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Hs
		177233 TCPG_HUMAN (3-528): 0: 559: 27.96		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Sc
		693035 TCPH_YEAST (2-528): 0: 543: 25.84		RPD3_YEAST (8-421): 0: 580: 61.48
+	Hs
		177231 TCPE_HUMAN (3-528): 0: 548: 30.47		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Sp
		140638 TCPH_SCHPO (3-527): 0: 560: 26.27		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sp
		140519 TCPG_SCHPO (2-527): 0: 555: 28.76		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sc
		761039 TCPZ_YEAST (3-530): 0: 579: 56.75		HOS2_YEAST (10-411): 2.72e-171: 491: 50.00
+	Sc
		792389 TCPH_YEAST (2-528): 0: 543: 25.84		HOS2_YEAST (10-411): 2.72e-171: 491: 50.00
+	Hs
		1306720 TCPH_HUMAN (2-530): 0: 576: 27.93		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		826927 TCPG_HUMAN (3-528): 0: 559: 27.96		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		821448 TCPE_HUMAN (3-528): 0: 548: 30.47		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78