HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.954

The method score is based on:

Property Details
Experiments 27684187, 26496610, 9535896, 11712088, 34079125, 36652389, 17510365
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Arm~Arm
Common GO terms GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 15 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 745
Hs

1 781
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Last updated: 11Aug2025