HitPredict

Interactor 1: RCC1 (P18754)
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)
Gene: RCC1

Interactor 2: RANB3 (Q9H6Z4)
Ran-binding protein 3 (RanBP3)
Gene: RANBP3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

Property	Details
Experiments	11932251, 9637251
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0031267 - small GTPase binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 421 Hs			1 567
+	Hs
		483381 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RGPD1_HUMAN (237-548): 1.99e-36: 147: 17.30
+	Hs
		152761 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RGPD8_HUMAN (246-547): 9.23e-36: 145: 16.72
+	Hs
		578469 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RGPD5_HUMAN (246-548): 1.48e-35: 144: 16.35
+	Hs
		63873 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RGPD3_HUMAN (246-548): 6.71e-35: 143: 16.03
+	Hs
		578395 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RBP2_HUMAN (248-564): 3.22e-33: 138: 17.52
+	Hs
		578387 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RANG_HUMAN (355-549): 1.54e-34: 131: 17.73
+	Sc
		601760 RCC1_YEAST (192-419): 1.22e-30: 124: 18.85		YRB2_YEAST (177-510): 1.46e-30: 123: 20.24
+	Sc
		601745 RCC1_YEAST (192-419): 1.22e-30: 124: 18.85		NUP2_YEAST (120-512): 1.75e-28: 122: 14.25
+	Sc
		601761 RCC1_YEAST (192-419): 1.22e-30: 124: 18.85		YRB1_YEAST (330-515): 9.14e-24: 101: 18.75