Interactor 1: PLCG1 (P19174)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)
Gene: PLCG1

Interactor 2: RASA1 (P20936)
Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP)
Gene: RASA1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 8977179, 9743338, 9020117
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C2~C2, C2~SH2, PH~PH, PH~SH3_1, C2~PI-PLC-X, C2~PI-PLC-Y, SH2~SH2, SH2~SH3_1, SH3_1~SH3_1
Common GO terms GO:0001726 - ruffle
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 1290
Hs

1 1047
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024