HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (EC 3.6.5.2) (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: KCC2G (Q13555)
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)
Gene: CAMK2G

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 558
+	Hs
		581030 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		KCC2D_HUMAN (1-558): 8.99e-176: 507: 63.26
+	Hs
		988474 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		MARK2_HUMAN (2-501): 2.94e-139: 424: 25.59
+	Hs
		581132 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		MARK2_HUMAN (2-501): 2.94e-139: 424: 25.59
+	Hs
		601344 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		MARK2_HUMAN (2-501): 2.94e-139: 424: 25.59
+	Hs
		953523 RAC3_HUMAN (1-191): 4.97e-80: 238: 89.01		MARK2_HUMAN (2-501): 2.94e-139: 424: 25.59
+	Hs
		1015546 RHOG_HUMAN (1-192): 5.1e-79: 235: 70.83		MARK2_HUMAN (2-501): 2.94e-139: 424: 25.59
+	Hs
		955318 CDC42_HUMAN (1-192): 1.66e-78: 234: 68.75		MARK2_HUMAN (2-501): 2.94e-139: 424: 25.59
+	Hs
		962195 RHOA_HUMAN (5-192): 1.59e-77: 231: 54.26		MARK2_HUMAN (2-501): 2.94e-139: 424: 25.59
+	Hs
		466323 RHOC_HUMAN (5-192): 3.56e-75: 225: 54.79		MARK2_HUMAN (2-501): 2.94e-139: 424: 25.59
+	Hs
		168669 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		CSKP_HUMAN (10-308): 2.85e-83: 280: 46.08
+	Hs
		168627 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		CSKP_HUMAN (10-308): 2.85e-83: 280: 46.08
+	Hs
		168631 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		CSKP_HUMAN (10-308): 2.85e-83: 280: 46.08
+	Hs
		168672 RHOG_HUMAN (1-192): 5.1e-79: 235: 70.83		CSKP_HUMAN (10-308): 2.85e-83: 280: 46.08
+	Hs
		168664 CDC42_HUMAN (1-192): 1.66e-78: 234: 68.75		CSKP_HUMAN (10-308): 2.85e-83: 280: 46.08
+	Hs
		581028 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		KCC2B_HUMAN (287-558): 1.88e-58: 207: 49.29